Article
Classification of OprD sequence and correlation with antimicrobial activity of carbapenem agents in Pseudomonas aeruginosa clinical isolates collected in Japan.
Microbiology and immunology - 1 Jul 2009
Sanbongi Yumiko, Shimizu Atsuyuki, Suzuki Takahisa, Nagaso Hiroshi, Ida Takashi, Maebashi Kazunori, Gotoh Naomasa
Abstract excerpt
A total of 99 clinical isolates of metallo-ss-lactamase-negative Pseudomonas aeruginosa collected in Japan between 1998 and 2001 were studied for their susceptibilities to carbapenem agents and corresponding oprD gene mutations. The OprD sequence of each strain was grouped into two major classes, based on the pattern of alterations. Eighty strains (80.8%) were so-called 'full length type', whose OprD proteins...
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