Structural characterization of CO-inhibited Mo-nitrogenase by combined application of nuclear resonance vibrational spectroscopy, extended X-ray absorption fine structure, and density functional theory: new insights into the effects of CO binding and the role of the interstitial atom.

doi:10.1021/ja505720m

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Article

Structural characterization of CO-inhibited Mo-nitrogenase by combined application of nuclear resonance vibrational spectroscopy, extended X-ray absorption fine structure, and density functional theory: new insights into the effects of CO binding and the role of the interstitial atom.

Journal of the American Chemical Society - 12 Nov 2014

Scott Aubrey D, Pelmenschikov Vladimir, Guo Yisong, Yan Lifen, Wang Hongxin, George Simon J, Dapper Christie H, Newton William E, Yoda Yoshitaka, Tanaka Yoshihito, Cramer Stephen P

Abstract excerpt

The properties of CO-inhibited Azotobacter vinelandii (Av) Mo-nitrogenase (N2ase) have been examined by the combined application of nuclear resonance vibrational spectroscopy (NRVS), extended X-ray absorption fine structure (EXAFS), and density functional theory (DFT). Dramatic changes in the NRVS are seen under high-CO conditions, especially in a 188 cm(-1) mode associated with symmetric breathing of the central...

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PMID: 25275608
DOI: 10.1021/ja505720m
PMCID: PMC4235365

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