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Article

Understanding and Targeting Alkylator Resistance in Glioblastoma

30 Sept 2014

Abstract excerpt

Abstract Summary: Alkylating chemotherapy is the mainstay in the treatment of pediatric and adult glioblastoma despite primary and acquired resistance and scientific efforts to precisely define therapies for individual patients. A focus on non–MGMT-mediated temozolomide resistance for pediatric glioblastoma suggests options for new drug combinations. Cancer Discov; 4(10); 1120–2. ©2014 AACR. See related article...

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Identifiers

PMID: 25274683
DOI: 10.1158/2159-8290.cd-14-0918

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Understanding and Targeting Alkylator Resistance in GlioblastomaPMID 25274683Read ↗

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Temozolomide resistance in glioblastoma multiformeSemantic proximity Read ↗

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