Article
Causal relevance of circulating adiponectin with cancer: a meta-analysis implementing Mendelian randomization.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2015
Pei Yuan, Xu Yue, Niu Wenquan
Abstract excerpt
Some studies have observed a lower circulating level of adiponectin in cancer patients, but whether this observation is causal remains unresolved. We therefore undertook a meta-analysis implementing Mendelian randomization to exploit the causal relevance of circulating adiponectin with cancer by using multiple polymorphisms in adiponectin encoded gene ADIPOQ as instrumental variables. Eligible articles were...
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