Article
Multiple mutations in the para-sodium channel gene are associated with pyrethroid resistance in Rhipicephalus microplus from the United States and Mexico.
Parasites & vectors - 1 Oct 2014
Stone Nathan E, Olafson Pia U, Davey Ronald B, Buckmeier Greta, Bodine Deanna, Sidak-Loftis Lindsay C, Giles John R, Duhaime Roberta, Miller Robert J, Mosqueda Juan, Scoles Glen A, Wagner David M, Busch Joseph D
Abstract excerpt
BACKGROUND: Acaricide resistant Rhipicephalus microplus populations have become a major problem for many cattle producing areas of the world. Pyrethroid resistance in arthropods is typically associated with mutations in domains I, II, III, and IV of voltage-gated sodium channel genes. In R. microplus, known resistance mutations include a domain II change (C190A) in populations from Australia, Africa, and South...
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