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The genome of Coxiella burnetii Z3055, a clone linked to the Netherlands Q fever outbreaks, provides evidence for the role of drift in the emergence of epidemic clones.

Comparative immunology, microbiology and infectious diseases - 1 Dec 2014

D'Amato Felicetta, Rouli Laetitia, Edouard Sophie, Tyczka Judith, Million Matthieu, Robert Catherine, Nguyen Thi Tien, Raoult Didier

Abstract excerpt

Coxiella burnetii is a pathogen causing Q fever. The aim of our work was to study Z3055, a strain that is genotypically related to the strain causing the Netherlands outbreak. We compared Z3055 to 5 other completed genomes available in GenBank. We calculated the blast score ratio (BSR) to analyze genetic differences among the strains. The ratio core genome/pangenome was 98% likely other bacteria with closed...

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PMID: 25249233
DOI: 10.1016/j.cimid.2014.08.003

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NMI

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