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Article

Collagen peptide and vitamin C additively attenuate age-related skin atrophy in Sod1-deficient mice.

Bioscience, biotechnology, and biochemistry - 1 Jan 2014

Shibuya Shuichi, Ozawa Yusuke, Toda Toshihiko, Watanabe Kenji, Tometsuka Chisa, Ogura Takayuki, Koyama Yoh-ichi, Shimizu Takahiko

Abstract excerpt

Age-related skin thinning is correlated with a decrease in the content of collagen in the skin. Accumulating evidence suggests that collagen peptide (CP) and vitamin C (VC) transcriptionally upregulate type I collagen in vivo. However, the additive effects of CP and VC on age-related skin changes remain unclear. We herein demonstrate that CP and a VC derivative additively corrected age-related skin thinning via...

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Identifiers

PMID: 25229861
DOI: 10.1080/09168451.2014.915728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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