Article
miR149 rs71428439 polymorphism and risk of clear cell renal cell carcinoma: a case-control study.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2014
Wang Zhigang, Wei Meng, Ren Yi, Liu Hua, Wang Meng, Shi Kehui, Jiang Hongli
Abstract excerpt
Clear cell renal cell carcinoma (CCRCC) is the most common subtype of renal cell cancer and accounts for 70 % of renal cell cancer. CCRCC remains an enigmatic tumor type, as the molecular genetic mechanisms are still unclear. MicroRNA (miR) 149 functions as a tumor suppressor and plays an important role in the carcinogenesis of renal cells. In this study, we enrolled 1,000 CCRCC patients and 1,000 cancer-free...
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