Article
Pre-clinical immunogenicity of human papillomavirus alpha-7 and alpha-9 major capsid proteins.
Vaccine - 12 Nov 2014
Bissett Sara L, Mattiuzzo Giada, Draper Eve, Godi Anna, Wilkinson Dianna E, Minor Philip, Page Mark, Beddows Simon
Abstract excerpt
Human papillomavirus (HPV) vaccines confer protection against the oncogenic genotypes HPV16 and HPV18 through the generation of type-specific neutralizing antibodies raised against the constituent virus-like particles (VLP) based upon the major capsid proteins (L1) of these genotypes. The vaccines also confer a degree of cross-protection against some genetically related types from the Alpha-9 (HPV16-like: HPV31,...
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