Article
A ten-year retrospective analysis of the distribution, use and phenotypic characteristics of the LAD2 human mast cell line.
International archives of allergy and immunology - 1 Jan 2014
Kirshenbaum Arnold S, Petrik Amy, Walsh Rosemary, Kirby Tara L, Vepa Sury, Wangsa Danny, Ried Thomas, Metcalfe Dean D
Abstract excerpt
BACKGROUND: In 2003, this laboratory published an account of the human mast cell line LAD2 (Laboratory of Allergic Diseases 2) that expressed FcεRI, responded to recombinant human stem cell factor (rhSCF) and resembled CD34+-derived human mast cells. LAD2 cells have now been distributed worldwide. To study the impact of this transfer, we analyzed the number of investigators receiving LAD2 cells and resulting...
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