Article
Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
Nucleic acids research - 1 Jan 2014
Xu Yifeng, Gan Eng-Seng, Zhou Jie, Wee Wan-Yi, Zhang Xiaoyu, Ito Toshiro
Abstract excerpt
Trimethylation of lysine 36 of histone H3 (H3K36me3) is found to be associated with various transcription events. In Arabidopsis, the H3K36me3 level peaks in the first half of coding regions, which is in contrast to the 3'-end enrichment in animals. The MRG15 family proteins function as 'reader' proteins by binding to H3K36me3 to control alternative splicing or prevent spurious intragenic transcription in...
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