Article
The Mycobacterium avium ssp. paratuberculosis specific mptD gene is required for maintenance of the metabolic homeostasis necessary for full virulence in mouse infections.
Frontiers in cellular and infection microbiology - 1 Jan 2014
Meißner Thorsten, Eckelt Elke, Basler Tina, Meens Jochen, Heinzmann Julia, Suwandi Abdulhadi, Oelemann Walter M R, Trenkamp Sandra, Holst Otto, Weiss Siegfried, Bunk Boyke, Spröer Cathrin, Gerlach Gerald-F, Goethe Ralph
Abstract excerpt
Mycobacterium avium subspecies paratuberculosis (MAP) causes Johne's disease, a chronic granulomatous enteritis in ruminants. Furthermore, infections of humans with MAP have been reported and a possible association with Crohn's disease and diabetes type I is currently discussed. MAP owns large sequence polymorphisms (LSPs) that were exclusively found in this mycobacteria species. The relevance of these LSPs in...
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