Article
The BGN and ACAN genes and carpal tunnel syndrome.
Gene - 10 Nov 2014
Burger Marilize C, De Wet Hanli, Collins Malcolm
Abstract excerpt
The causes of idiopathic carpal tunnel syndrome (CTS) remain unknown and the involvement of the tendons within the carpal tunnel structure in the aetiology of CTS cannot be excluded. Variants within the COL5A1 gene, an important regulator of fibril assembly in tendons, have previously been associated with modulating the risk of CTS. Furthermore, proteoglycans are also important structural components of tendons...
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