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Article

KRAS status and resistance to epidermal growth factor receptor tyrosine-kinase inhibitor treatment in patients with metastatic colorectal cancer: a meta-analysis.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland - 1 Nov 2014

Li W, Shi Q, Wang W, Liu J, Ren J, Li Q, Hou F

Abstract excerpt

AIM: This study reviewed the association between KRAS mutation and resistance to treatment with epidermal growth factor receptor (EGFR) tyrosine-kinase inhibitors (TKIs) in patients with metastatic colorectal cancer (mCRC). METHOD: A search was carried out of PubMed, MEDLINE, EMBASE and the Cochrane Library databases (to November 2013) without language restrictions. RESULTS: Ten studies were included in the final...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25155261
DOI: 10.1111/codi.12749

Genes

KRAS
EGFR

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