Article
Mycobacterium simiae infection in two unrelated patients with different forms of inherited IFN-γR2 deficiency.
Journal of clinical immunology - 1 Nov 2014
Martínez-Barricarte Rubén, Megged Orli, Stepensky Polina, Casimir Pierre, Moncada-Velez Marcela, Averbuch Diana, Assous Marc Victor, Abuzaitoun Omar, Kong Xiao-Fei, Pedergnana Vincent, Deswarte Caroline, Migaud Mélanie, Rose-John Stefan, Itan Yuval, Boisson Bertrand, Belkadi Aziz, Conti Francesca, Abel Laurent, Vogt Guillaume, Boisson-Dupuis Stephanie, Casanova Jean-Laurent, Bustamante Jacinta
Abstract excerpt
Interferon-γ receptor 2 (IFN-γR2) deficiency is a rare primary immunodeficiency characterized by predisposition to infections with weakly virulent mycobacteria, such as environmental mycobacteria and BCG vaccines. We describe here two children with IFN-γR2 deficiency, from unrelated, consanguineous kindreds of Arab and Israeli descent. The first patient was a boy who died at the age of 4.5 years, from recurrent,...
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