Article
Metabolic phenotyping reveals a lipid mediator response to ionizing radiation.
Journal of proteome research - 5 Sept 2014
Laiakis Evagelia C, Strassburg Katrin, Bogumil Ralf, Lai Steven, Vreeken Rob J, Hankemeier Thomas, Langridge James, Plumb Robert S, Fornace Albert J, Astarita Giuseppe
Abstract excerpt
Exposure to ionizing radiation has dramatically increased in modern society, raising serious health concerns. The molecular response to ionizing radiation, however, is still not completely understood. Here, we screened mouse serum for metabolic alterations following an acute exposure to γ radiation using a multiplatform mass-spectrometry-based strategy. A global, molecular profiling revealed that mouse serum...
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