Article
Candidate prognostic markers in breast cancer: focus on extracellular proteases and their inhibitors
1 Jul 2014
Abstract excerpt
The extracellular matrix (ECM) is the complex network of proteins that surrounds cells in multicellular organisms. Due to its diverse nature and composition, the ECM has a multifaceted role in both normal tissue homeostasis and pathophysiology. It provides structural support, segregates tissues from one another, and regulates intercellular communication. Furthermore, the ECM sequesters a wide range of growth...
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