Article
Developmental pathways activated in melanocytes and melanoma.
Archives of biochemistry and biophysics - 1 Dec 2014
Liu Jianglan, Fukunaga-Kalabis Mizuho, Li Ling, Herlyn Meenhard
Abstract excerpt
Cutaneous malignant melanomas originate primarily within epidermal melanocytic cells. Melanoma cells share many characteristics with melanocyte precursors, suggesting that melanoma cells utilize the developmental programs of their normal counterpart for their own progression. The pigmentation sys...
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