Article
Strategy revealing phenotypic differences among synthetic oscillator designs.
ACS synthetic biology - 19 Sept 2014
Lomnitz Jason G, Savageau Michael A
Abstract excerpt
Considerable progress has been made in identifying and characterizing the component parts of genetic oscillators, which play central roles in all organisms. Nonlinear interaction among components is sufficiently complex that mathematical models are required to elucidate their elusive integrated behavior. Although natural and synthetic oscillators exhibit common architectures, there are numerous differences that...
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