Article
Null genotype of GSTM1 and GSTT1 may contribute to susceptibility to male infertility with impaired spermatogenesis in Chinese population.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Mar 2013
Xu Xiao-Bo, Liu Shuo-Ran, Ying Hou-Qun, A Zhou-Cun
Abstract excerpt
Glutathione-S-transferases (GSTs) play a protective role during spermatogenesis and GST genes may be involved in impaired spermatogenesis. A case-control study was performed to explore the association of genes GSTM1 and GSTT1, two members of GST gene family, with spermatogenesis impairment. The deletion polymorphism distribution of genes GSTM1 and GSTT1 was investigated in 353 patients with azoospermia or...
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