Trends and predictors of transmitted drug resistance (TDR) and clusters with TDR in a local Belgian HIV-1 epidemic.

doi:10.1371/journal.pone.0101738

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Article

Trends and predictors of transmitted drug resistance (TDR) and clusters with TDR in a local Belgian HIV-1 epidemic.

PloS one - 1 Jan 2014

Pineda-Peña Andrea-Clemencia, Schrooten Yoeri, Vinken Lore, Ferreira Fossie, Li Guangdi, Trovão Nídia Sequeira, Khouri Ricardo, Derdelinckx Inge, De Munter Paul, Kücherer Claudia, Kostrikis Leondios G, Nielsen Claus, Littsola Kirsi, Wensing Annemarie, Stanojevic Maja, Paredes Roger, Balotta Claudia, Albert Jan, Boucher Charles, Gomez-Lopez Arley, Van Wijngaerden Eric, Van Ranst Marc, Vercauteren Jurgen, Vandamme Anne-Mieke, Van Laethem Kristel

Abstract excerpt

We aimed to study epidemic trends and predictors for transmitted drug resistance (TDR) in our region, its clinical impact and its association with transmission clusters. We included 778 patients from the AIDS Reference Center in Leuven (Belgium) diagnosed from 1998 to 2012. Resistance testing was performed using population-based sequencing and TDR was estimated using the WHO-2009 surveillance list. Phylogenetic...

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PMID: 25003369
DOI: 10.1371/journal.pone.0101738
PMCID: PMC4086934

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