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Article

Interplay between polymorphisms in the endothelial nitric oxide synthase (eNOS) gene and metabolic syndrome in determining the risk of ischemic stroke in Koreans.

Journal of the neurological sciences - 15 Sept 2014

Kang Min Kyu, Kim Ok Joon, Jeon Young Joo, Kim Hyun Sook, Oh Seung Hun, Kim Jin Kwon, Kim Eo Jin, Hwang Tae Sun, Kim Nam Keun

Abstract excerpt

BACKGROUND: Endothelial nitric oxide synthase (eNOS) gene variants are known to play a role in atherosclerotic development. However, whether interplay between eNOS polymorphisms and metabolic syndrome (MetS) affects ischemic stroke (IS) risk has yet to be discovered. We investigated whether the combined effects of eNOS polymorphisms and MetS influence ischemic stroke risk in Koreans. METHODS: We genotyped the...

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PMID: 24976532
DOI: 10.1016/j.jns.2014.06.020

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