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Article

Screening candidate metastasis-associated genes in three-dimensional HCC spheroids with different metastasis potential.

International journal of clinical and experimental pathology - 1 Jan 2014

Chen Rongxin, Dong Yinying, Xie Xiaoying, Chen Jie, Gao Dongmei, Liu Yinkun, Ren Zhenggang, Cui Jiefeng

Abstract excerpt

PURPOSE: Previously, we have established a tissue-like HCC spheroid which better mirrors the biological features of tumorigenesis and metastasis. This study was to find out metastasis-associated genes between two 3D HCC spheroids with different metastasis potential using comparative PCR arrays. MATERIALS AND METHODS: Two HCC spheroids derived from high-metastatic MHCC97H cells and low-metastatic Hep3B cells were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24966965
PMCID: PMC4069880

Genes

CTNND2
SPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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