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Article

WHO-histological criteria for myeloproliferative neoplasms: reproducibility, diagnostic accuracy and correlation with gene mutations and clinical outcomes.

British journal of haematology - 1 Sept 2014

Alvarez-Larrán Alberto, Ancochea Agueda, García Mar, Climent Fina, García-Pallarols Francesc, Angona Anna, Senín Alicia, Barranco Carlos, Martínez-Avilés Luz, Serrano Sergio, Bellosillo Beatriz, Besses Carlos

Abstract excerpt

Bone marrow histology is included in the diagnostic criteria of myeloproliferative neoplasms (MPNs). However, some concerns have emerged about its reproducibility. To evaluate the diagnostic accuracy of histology and to assess its correlation with presence of mutations and clinical outcomes, two pathologists reviewed the bone marrow biopsies corresponding to 211 patients with MPN. Despite the low agreement in the...

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Identifiers

PMID: 24957246
DOI: 10.1111/bjh.12990

Genes

CALR
JAK2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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