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Article

Polymorphisms in translesion polymerase genes influence treatment outcome in malignant mesothelioma.

Pharmacogenomics - 1 May 2014

Goričar Katja, Kovač Viljem, Dolžan Vita

Abstract excerpt

AIM: We evaluated the influence of genetic variability in translesion polymerases REV1 and REV3L on the outcome of cisplatin treatment in malignant mesothelioma patients. MATERIALS & METHODS: In total, 139 malignant mesothelioma patients were genotyped for seven tag SNPs in REV1 and REV3L. Logistic regression and Cox regression were used to assess the influence of SNPs on treatment outcome. RESULTS: Polymorphic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24956248
DOI: 10.2217/pgs.14.14

Genes

REV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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