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Mutations in the 50S ribosomal subunit of Brachyspira hyodysenteriae associated with altered minimum inhibitory concentrations of pleuromutilins.

Veterinary microbiology - 6 Aug 2014

Hillen Sonja, Willems Hermann, Herbst Werner, Rohde Judith, Reiner Gerald

Abstract excerpt

Brachyspira hyodysenteriae, the causative agent of swine dysentery, is responsible for severe mucohaemorrhagic colitis with considerable financial loss to worldwide swine production. Antimicrobial resistance against macrolides and lincosamides is widespread and the mechanisms are well known. Currently, the most common treatment for swine dysentery is the use of pleuromutilins and resistance to these drugs also is...

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PMID: 24948419
DOI: 10.1016/j.vetmic.2014.04.021

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