Article
The genetic diversity of cereulide biosynthesis gene cluster indicates a composite transposon Tnces in emetic Bacillus weihenstephanensis.
BMC microbiology - 7 Jun 2014
Mei Xiaofen, Xu Kai, Yang Lingling, Yuan Zhiming, Mahillon Jacques, Hu Xiaomin
Abstract excerpt
BACKGROUND: Cereulide is a cyclic dodecadepsipeptide ionophore, produced via non-ribosomal peptide synthetases (NRPS), which in rare cases can lead to human death. Early studies had shown that emetic toxin formation belongs to a homogeneous group of Bacillus cereus sensu stricto and the genetic d...
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