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Article

Polymorphisms at the 3' untranslated region of SLC11A1 gene are associated with protection to Brucella infection in goats.

Veterinary immunology and immunopathology - 15 Aug 2014

Iacoboni Paola A, Hasenauer Flavia C, Caffaro M Eugenia, Gaido Analia, Rossetto Cristina, Neumann Roberto D, Salatin Antonio, Bertoni Emiliano, Poli Mario A, Rossetti Carlos A

Abstract excerpt

Goats are susceptible to brucellosis and the detection of Brucella-infected animals is carried out by serological tests. In other ruminant species, polymorphisms in microsatellites (Ms) of 3' untranslated region (3'UTR) of the solute carrier family 11 member A1 (SLC11A1) gene were associated with resistance to Brucella abortus infection. Goats present two polymorphic Ms at the 3'UTR end of SLC11A1 gene, called...

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PMID: 24906349
DOI: 10.1016/j.vetimm.2014.05.007

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