Article
Synchronous occurrence of medullary and papillary carcinoma of the thyroid in a patient with cutaneous melanoma: determination of BRAFV600E in peripheral blood and tissues. Report of a case and review of the literature.
Endocrine pathology - 1 Sept 2014
Fibbi Benedetta, Pinzani Pamela, Salvianti Francesca, Rossi Matteo, Petrone Luisa, De Feo Maria Laura, Panconesi Roberto, Vezzosi Vania, Bianchi Simonetta, Simontacchi Gabriele, Mangoni Monica, Pertici Maurizio, Forti Gianni, Pupilli Cinzia
Abstract excerpt
The purpose of this study is to describe a case of concurrent medullary and papillary thyroid carcinoma (MTC and PTC) and cutaneous melanoma and to analyze BRAF(V600E) mutation in plasma and tissues. We report the clinical history and the laboratory, imaging, and histopathological findings of a 47-year-old man affected by multinodular goiter. BRAF(V600E)-mutated DNA was quantified in plasma samples and in cancer...
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