Article
Human Y-chromosome SNP characterization by multiplex amplified product-length polymorphism analysis.
Electrophoresis - 1 Sept 2014
Medina Laura Smeldy Jurado, Muzzio Marina, Schwab Marisol, Costantino María Leticia Bravi, Barreto Guillermo, Bailliet Graciela
Abstract excerpt
We designed an allele-specific amplification protocol to optimize Y-chromosome SNP typing, which is an unavoidable step for defining the phylogenetic status of paternal lineages. It allows the simultaneous highly specific definition of up to six mutations in a single reaction by amplification fragment length polymorphism (AFLP) without the need of specialized equipment, at a considerably lower cost than that...
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