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An efficient multiplex genotyping approach for detecting the major worldwide human Y-chromosome haplogroups.

International journal of legal medicine - 1 Nov 2011

van Oven Mannis, Ralf Arwin, Kayser Manfred

Abstract excerpt

The Y chromosome is paternally inherited and therefore serves as an evolutionary marker of patrilineal descent. Worldwide DNA variation within the non-recombining portion of the Y chromosome can be represented as a monophyletic phylogenetic tree in which the branches (haplogroups) are defined by at least one SNP. Previous human population genetics research has produced a wealth of knowledge about the worldwide...

Topics

Chromosomes, Human, Y
Genetics, Population
Genotype
Haplotypes
Humans
Male
Polymerase Chain Reaction
Polymorphism, Single Nucleotide

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21785904
DOI: 10.1007/s00414-011-0605-2
PMCID: PMC3192277

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