Article
Bacterial actin MreB forms antiparallel double filaments.
eLife - 2 May 2014
van den Ent Fusinita, Izoré Thierry, Bharat Tanmay Am, Johnson Christopher M, Löwe Jan
Abstract excerpt
Filaments of all actin-like proteins known to date are assembled from pairs of protofilaments that are arranged in a parallel fashion, generating polarity. In this study, we show that the prokaryotic actin homologue MreB forms pairs of protofilaments that adopt an antiparallel arrangement in vitro and in vivo. We provide an atomic view of antiparallel protofilaments of Caulobacter MreB as apparent from crystal...
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