Article
Analysis of clinical isolates of Helicobacter pylori in Pakistan reveals high degrees of pathogenicity and high frequencies of antibiotic resistance.
Helicobacter - 1 Oct 2014
Rasheed Faisal, Campbell Barry James, Alfizah Hanafiah, Varro Andrea, Zahra Rabaab, Yamaoka Yoshio, Pritchard David Mark
Abstract excerpt
BACKGROUND: Antibiotic resistance in Helicobacter pylori contributes to failure in eradicating the infection and is most often due to point and missense mutations in a few key genes. METHODS: The antibiotic susceptibility profiles of H. pylori isolates from 46 Pakistani patients were determined by Etest. Resistance and pathogenicity genes were amplified, and sequences were analyzed to determine the presence of...
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