The metabotropic glutamate receptor subtype 7 rs3792452 polymorphism is associated with the response to methylphenidate in children with attention-deficit/hyperactivity disorder.

Abstract excerpt

OBJECTIVE: The purpose of this study was to investigate the association between the metabotropic glutamate receptor subtype 7 (mGluR7) gene (GRM7) polymorphism and treatment response to methylphenidate in Korean children with attention-deficit/hyperactivity disorder (ADHD). METHODS: We enrolled 175 medication-naïve children with ADHD in an open-label 8 week trial of methylphenidate. The participants were...

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