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Huaier suppresses proliferation and induces apoptosis in human pulmonary cancer cells via upregulation of miR‐26b‐5p

8 May 2014

Abstract excerpt

Various studies have reported that Huaier possesses anti-tumor effects. However, the mechanisms are not completely elucidated. Here, we found 66 differentially expressed miRNAs in Huaier-treated pulmonary adenocarcinoma A549 cells, with upregulation of miR-26b-5p. Transfection of A549 cells with miR-26b-5p mimic inhibited proliferation and induced apoptosis, while transfection of Huaier-treated A549 cells with a...

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PMID: 24815696
DOI: 10.1016/j.febslet.2014.04.044

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