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Article

Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate.

The oncologist - 1 Jun 2014

Fathi Amir T, Sadrzadeh Hossein, Comander Amy H, Higgins Michaela J, Bardia Aditya, Perry Ashley, Burke Meghan, Silver Regina, Matulis Christina R, Straley Kimberly S, Yen Katharine E, Agresta Sam, Kim Hyeryun, Schenkein David P, Borger Darrell R

Abstract excerpt

Mutations in the IDH1 and IDH2 (isocitrate dehydrogenase) genes have been discovered across a range of solid-organ and hematologic malignancies, including acute myeloid leukemia, glioma, chondrosarcoma, and cholangiocarcinoma. An intriguing aspect of IDH-mutant tumors is the aberrant production a...

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Source

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Identifiers

PMID: 24760710
DOI: 10.1634/theoncologist.2013-0417
PMCID: PMC4041671

Genes

IDH1
IDH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24760710-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate.PMID 24760710Read ↗

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