Article
Beyond EGFR TKI in EGFR-mutant non-small cell lung cancer patients: main challenges still to be overcome.
Cancer treatment reviews - 1 Jul 2014
Remon J, Morán T, Reguart N, Majem M, Carcereny E, Lianes P
Abstract excerpt
First line epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI) is the standard treatment in advanced EGFR-mutant Non Small Cell Lung Cancer (NSCLC) patients, with an improvement in response rate, progression free survival, and quality of life compared with upfront chemotherapy. However, in the real world, EGFR mutation results often return positive once chemotherapy has been started. Different...
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