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Article

Asiaticoside, a component of Centella asiatica, inhibits melanogenesis in B16F10 mouse melanoma

16 Apr 2014

Abstract excerpt

Melanogenesis is the process of generating pigmentation via melanin synthesis and delivery. Three key enzymes, tyrosinase, tyrosinase-related protein 1 (TRP1) and TRP2, metabolize melanin from L-tyrosine. Melanin synthesizing enzymes are regulated by microphthalmia-associated transcription factor (MITF). The titrated extract of Centella asiatica (TECA) contains the major components asiatic acid, asiaticoside and...

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Identifiers

PMID: 24756377
DOI: 10.3892/mmr.2014.2159

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