Article
Widespread differential maternal and paternal genome effects on fetal bone phenotype at mid-gestation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 2014
Xiang Ruidong, Lee Alice M C, Eindorf Tanja, Javadmanesh Ali, Ghanipoor-Samami Mani, Gugger Madeleine, Fitzsimmons Carolyn J, Kruk Zbigniew A, Pitchford Wayne S, Leviton Alison J, Thomsen Dana A, Beckman Ian, Anderson Gail I, Burns Brian M, Rutley David L, Xian Cory J, Hiendleder Stefan
Abstract excerpt
Parent-of-origin-dependent (epi)genetic factors are important determinants of prenatal development that program adult phenotype. However, data on magnitude and specificity of maternal and paternal genome effects on fetal bone are lacking. We used an outbred bovine model to dissect and quantify ef...
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