Article
Circulating HFMD-associated coxsackievirus A16 is genetically and phenotypically distinct from the prototype CV-A16.
PloS one - 1 Jan 2014
Wei Wei, Guo Haoran, Li Jingliang, Ren Sangsang, Wei Zhenhong, Bao Wanguo, Hu Xiaoming, Zhao Ke, Zhang Wenyan, Zhou Yulai, Sun Fei, Markham Richard, Yu Xiao-Fang
Abstract excerpt
Human enteroviruses (HEV) have been linked to hand, foot, and mouth disease (HFMD) in the Pacific and Southeast Asia for decades. Many cases of HFMD have been attributed to coxsackievirus A16 (CV-A16, CA16), based on only partial viral genome determination. Viral phenotypes are also poorly defined. Herein, we have genetically and phenotypically characterized multiple circulating CV-A16 viruses from HFMD patients...
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