Article
Association of group component genetic variations in COPD and COPD exacerbation in a Japanese population.
Respirology (Carlton, Vic.) - 1 May 2014
Ishii Takeo, Motegi Takashi, Kamio Koichiro, Gemma Akihiko, Kida Kozui
Abstract excerpt
BACKGROUND AND OBJECTIVE: Vitamin D supplementation can decrease the vulnerability to pulmonary infections. Therefore, it is speculated that the genes related to vitamin D metabolism are associated with an exacerbation-prone phenotype in chronic obstructive pulmonary disease (COPD). Because genetic variations of group component (GC) affect immunological capacity and serum vitamin D concentration, they could also...
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