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Article

Risk and severity of COPD is associated with the group-specific component of serum globulin 1F allele.

Chest - 1 Jan 2004

Ito Isao, Nagai Sonoko, Hoshino Yuma, Muro Shigeo, Hirai Toyohiro, Tsukino Mitsuhiro, Mishima Michiaki

Abstract excerpt

BACKGROUND: The finding that only 15 to 20% of cigarette smokers acquire COPD suggests that there is a genetic predisposition to the disease. Genetic polymorphism of the group-specific component of serum globulin (Gc-globulin), also known as vitamin-D-binding protein, is considered one of the can...

Read the complete abstract on PubMed

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Share to Alleles
Share to Forced Expiratory Volume
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Pulmonary Disease, Chronic Obstructive

Share to Tomography, X-Ray Computed

Share to Vitamin D-Binding Protein

Source

Identifiers

PMID: 14718422
DOI: 10.1378/chest.125.1.63

Genes

FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14718422-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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