Article
Competing targets of microRNA-608 affect anxiety and hypertension.
Human molecular genetics - 1 Sept 2014
Hanin Geula, Shenhar-Tsarfaty Shani, Yayon Nadav, Yau Yin Hoe, Hoe Yau Yin, Bennett Estelle R, Sklan Ella H, Rao Dabeeru C, Rankinen Tuomo, Bouchard Claude, Geifman-Shochat Susana, Shifman Sagiv, Greenberg David S, Soreq Hermona
Abstract excerpt
MicroRNAs (miRNAs) can repress multiple targets, but how a single de-balanced interaction affects others remained unclear. We found that changing a single miRNA-target interaction can simultaneously affect multiple other miRNA-target interactions and modify physiological phenotype. We show that m...
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