Autophagy and Cancer

doi:10.3390/cells1030520

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Autophagy and Cancer

13 Aug 2012

Abstract excerpt

Autophagy is a housekeeping survival mechanism with a protective function against stress conditions. However, when stress severity or duration increases, it may promote cell death. Paradoxically, autophagy favors cancer development, since cancer cells could enhance their proliferation potential (thus becoming able to resist anticancer therapy) thanks to the energetic supply provided by organelle degradation...

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PMID: 24710488
DOI: 10.3390/cells1030520

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