Article
Activity of sunitinib in extraskeletal myxoid chondrosarcoma.
European journal of cancer (Oxford, England : 1990) - 1 Jun 2014
Stacchiotti S, Pantaleo M A, Astolfi A, Dagrada G P, Negri T, Dei Tos A P, Indio V, Morosi C, Gronchi A, Colombo C, Conca E, Toffolatti L, Tazzari M, Crippa F, Maestro R, Pilotti S, Casali P G
Abstract excerpt
BACKGROUND: Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue sarcoma, marked by NR4A3 rearrangement. Herein we report on the activity of sunitinib in a series of 10 patients, strengthening what initially observed in two cases. PATIENTS AND METHODS: From July 2011, 10 patients with progressive metastatic translocated EMC have been consecutively treated with sunitinib 37.5mg/day, on a named-use...
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