Article
Disease-specific mutations in mature lymphoid neoplasms: recent advances.
Cancer science - 1 Jun 2014
Sakata-Yanagimoto Mamiko, Enami Terukazu, Yokoyama Yasuhisa, Chiba Shigeru
Abstract excerpt
Mature lymphoid neoplasms (MLN) are clinically and pathologically more complex than precursor lymphoid neoplasms. Until recently, molecular characterization of MLN was mainly based on cytogenetics/fluorescence in situ hybridization, allele copy number, and mRNA expression, approaches that yielded scanty gene mutation information. Use of massive parallel sequencing technologies has changed this outcome, and now...
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