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Article

Adverse prenatal environment and kidney development: implications for programing of adult disease.

Reproduction (Cambridge, England) - 1 Jun 2014

Dorey Emily S, Pantaleon Marie, Weir Kristy A, Moritz Karen M

Abstract excerpt

The 'developmental origins of health and disease' hypothesis suggests that many adult-onset diseases can be attributed to altered growth and development during early life. Perturbations during gestation can be detrimental and lead to an increased risk of developing renal, cardiovascular, metabolic, and neurocognitive dysfunction in adulthood. The kidney has emerged as being especially vulnerable to insult at...

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Identifiers

PMID: 24686455
DOI: 10.1530/REP-13-0478

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