Article
The common occurrence of epistasis in the determination of human pigmentation and its impact on DNA-based pigmentation phenotype prediction.
Forensic science international. Genetics - 1 Jul 2014
Pośpiech Ewelina, Wojas-Pelc Anna, Walsh Susan, Liu Fan, Maeda Hitoshi, Ishikawa Takaki, Skowron Małgorzata, Kayser Manfred, Branicki Wojciech
Abstract excerpt
The role of epistatic effects in the determination of complex traits is often underlined but its significance in the prediction of pigmentation phenotypes has not been evaluated so far. The prediction of pigmentation from genetic data can be useful in forensic science to describe the physical appearance of an unknown offender, victim, or missing person who cannot be identified via conventional DNA profiling....
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