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Article

Independent polled mutations leading to complex gene expression differences in cattle.

PloS one - 1 Jan 2014

Wiedemar Natalie, Tetens Jens, Jagannathan Vidhya, Menoud Annie, Neuenschwander Samuel, Bruggmann Rémy, Thaller Georg, Drögemüller Cord

Abstract excerpt

The molecular regulation of horn growth in ruminants is still poorly understood. To investigate this process, we collected 1019 hornless (polled) animals from different cattle breeds. High-density SNP genotyping confirmed the presence of two different polled associated haplotypes in Simmental and Holstein cattle co-localized on BTA 1. We refined the critical region of the Simmental polled mutation to 212 kb and...

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Cattle
Haplotypes
Heterozygote
Horns
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Long Noncoding

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Open in PubMed Open full text

Identifiers

PMID: 24671182
DOI: 10.1371/journal.pone.0093435
PMCID: PMC3966897

Genes

FOXL2
RXFP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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