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Article

Herceptin resistance database for understanding mechanism of resistance in breast cancer patients.

Scientific reports - 27 Mar 2014

Ahmad Sahil, Gupta Sudheer, Kumar Rahul, Varshney Grish C, Raghava Gajendra P S

Abstract excerpt

Monoclonal antibody Trastuzumab/Herceptin is considered as frontline therapy for Her2-positive breast cancer patients. However, it is not effective against several patients due to acquired or de novo resistance. In last one decade, several assays have been performed to understand the mechanism of Herceptin resistance with/without supplementary drugs. This manuscript describes a database HerceptinR, developed for...

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Share to Antibodies, Monoclonal, Humanized
Share to Antineoplastic Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Databases, Factual

Share to DNA Copy Number Variations

Share to Drug Resistance, Neoplasm

Share to Gene Expression Regulation, Neoplastic

Share to Trastuzumab

Source

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Identifiers

PMID: 24670875
DOI: 10.1038/srep04483
PMCID: PMC3967150

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